This presentation was given on wednesday, 7th of December 2011, 8 pm GMT, by Jonas Hannestad, @jhannestad, PhD student at Chemical and Biological Engineering at Chalmers University of Technology, Gothenburg. Jonas works with bio-inspired nanotechnology, with a particular focus on nano-scale photonic devices.
Links to further reading below.
TweeterJonas Hannestad |
Room#stu05 |
This is @ozonist tweeting to welcome you to yet another lecture on The Swedish Twitter University! | |
In just a few minutes Jonas Hannestad will take over the account and make a 25 tweet presentation of his intriguing field of research. | |
Before he starts let me remind you to add the #stu05 tag to any questions or comments you want to throw in. That way everybody can see them! | |
I would also like to say that the hashtag flow and Jonas’ tweets will be archived on the http://t.co/CFaoXxMh blog. | |
Now let’s enjoy this event titled “Nature as Technology: Strategies for Nano-Scale, DNA-Based Communication”. Take it away, Jonas! | |
Thanks @ozonist and good evening. My name is Jonas Hannestad an I’m a PhD student at Chalmers University of Technology, Gothenburg, Sweden. | |
I’m approaching the subject of bionanotechnology as a physical chemist, trying to develop photonic applications inspired by natural systems | |
In Tonight’s talk I will describe my research in brief and try to put it in a context of a novel view on technology as a whole. let’s begin | |
1. The ability to create technological devices on an ever-smaller scale forces us to question what we mean by technology | |
2. Nanotechnology deals with objects on the size scale of 1-100 nm, comparable to biological macromolecules such as proteins and DNA. | |
@Cotesia1 Tweets by Hannestad on bionanotechnology just started at @SVTwuni #STU05. Join us! |
|
3. Biotech. has defined biological organisms as objects of technology, utilized, for example, as production facilities or as disease models. | |
@cerreyes Nanosocieties. It’s a small world | @jhannestad about to start at @SvTwuni http://t.co/eW7yTuVh #stu05 |
|
4. Bioinspired nanotechnology does the same thing, but on a molecular level. Biomoluecules are used as building material for technology. | |
5. Utilizing self-assembly, nanometer-scale structures are built from the bottom-up to perform functions similar to natural ones. | |
6. The use of self-assembly and bottom-up design is an important difference to conventional technology which relies on top-down techniques. | |
7. Our research has two primary foci: assembly of nanometer-scale geometries from DNA and creation of photonic devices mimicking biology. | |
8. DNA is code. In nature, the genetic code is executed inside cells, which (eventually) leads to the production of proteins. | |
9. However, DNA can also be used to code other things, for instance structures in two and three dimensions. | |
10. DNA is a linear polymer with four constituents (A, T, G, C) which forms a double helix with a complementary counterpart (A-T, G-C). | |
11. By designing the complementarity pattern of multiple strands, they can be forced to fold into a specific shape http://t.co/8c2Mbfhm | |
12. Assemblies can also be designed to perform functions such as mechanical work or computation, building systems resembling neural networks | |
13. We want to modify DNA-based structures to perform nanoscale optical communication and to coordinate light driven chemical reactions. | |
14. This work is inspired by the way photosynthetic bacteria gather energy by directed energy migration through molecular assemblies | |
@cerreyes RT @SvTwuni 8. DNA is code. In nature, the genetic code is executed inside cells […] #stu05 #datathanatology |
|
15. Light-harvesting complexes are energetic funnels where energy absorbed in the outer parts flows towards the center. http://t.co/sHIzESTZ | |
16. This flow of energy can be mimicked by attachment of fluorescent dyes to DNA structures, controlling energy and positioning of the dyes. | |
17. Linear arrangement of dyes results in photonic wires where energy is transferred between the dyes, from end to end http://t.co/TJwkRqim | |
18. The input and output of the wire is a photon of high and low energy, respectively. Energy transfer occurs by dipole-dipole interaction. | |
19. The energy transfer mechanism is called FRET. FRET proceeds without emission of photons and has a distance dependence on the nm scale | |
@Cotesia1 @svtwuni: Is there a good reference (review) link for interesting points 14 & 15? Thanks! #STU05 |
|
20. The flow of energy in the systems can directed to separate outputs in controlled ways or regulated between on/off http://t.co/vpji0vxT | |
21. Inclusion of other modifications to DNA can introduce anchoring to bio-membranes or coupling of transferred energy to chem. reaction. | |
22. This coupling of energy transfer to electron transfer reactions is similar to the key mechanism in photosynthesis. http://t.co/wlCzZOvl | |
23. These examples show how self-assembled structures built from DNA can be used to coordinate a multitude of functionalities. | |
@ozonist @SvTwuni I lost tweet no 20… Just me? #stu05 |
|
24. A somewhat speculative application could be to use similar devices as a seamless interface between cells and conventional technology | |
@fredrikedin @ozonist I got it #stu05 @SvTwuni |
|
@Cotesia1 I added a link to a PNAS paper (where the images are from) in the description. I recommend the work by Klaus Schulten in general | |
25. The use of biomolecules and biological functions and design principles challenges our perceived boundaries between nature and technology | |
@ozonist I see it too, I can repost it if you like | |
That was the last tweet. I am now happy to answer any questions. Remember to use the #stu05 hashtag | |
@ozonist @SvTwuni Thank you, but I can see it in my phone… Weird. 🙂 #stu05 |
|
@Cotesia1 Interesting world. Attended a tweet lecture originating in Sweden – was then referred to work by person at UIUC. I think that’s gr8 #stu05 |
|
@ozonist @SvTwuni What does one need to hack these kind of technologies? #stu05 |
|
@Cotesia1 small world. The light harvesting complexes are really fascinating examples of nanoscale architecture in biology | |
@ozonist it depends on what one wants to do. Just creating DNA structures is fairly straightforward, albeit still a bit expensive #stu05 | |
@dromograf RT @Cotesia1: Interesting world. Attended a tweet lecture originating in Sweden – was then referred to work by person at UIUC. I think that’s gr8 #stu05 |
|
@ozonist the material is readily available and the designed can be done by hand (or using simple software). #stu05 | |
@ozonist since the structures self-assemble, all you have to do is to mix them in water. characterization can be another thing though #stu05 | |
@ozonist and if you want to add some functionalities things become more complex. most straightforward is the DNA origami I think | |
@ozonist and if you want to add some functionalities things become more complex. most straightforward is the DNA origami I think #stu05 | |
@cerreyes @SvTwuni Any possible application for architecture? e.g. surfaces harvesting light to feed energy inside buildings #stu05 |
|
@ozonist Thank you! Interesting. And very much a part of a maker paradigm rather than a tweaker paradigm… #STU05 |
|
@cerreyes I think, for that type of large-scale applications, these designs would not be very suitable. #stu05 | |
@cerreyes instead, I think it might be very interesting for researchers in the solar cell community to think more about architecture #stu05 | |
@ozonist Could you tell us a bit more about the “specualtive” seamless interface between cells and conventional technology application? #stu05 |
|
@cerreyes one possible application is in high density optical data storage. #stu05 | |
@cerreyes light would be gathered over a large are and transferred to a target molecule the interacts with an underlying surface #stu05 | |
@doktorsbloggen @SvTwuni @cerreyes as someone who could call herself a solar cell researcher, I agree with your achitecture point. #stu05 |
|
@ozonist since we use biomolecules, interaction with e.g. cells is possible, at the same time, we are using light as input and output #stu05 | |
@ozonist light signals is something that can be processed by conventional technology. #stu05 | |
@ozonist eventually it would be interesting to link this to the chemistry inside the cells, to probe and control the cell using light #stu05 | |
@ozonist and, finally, to effectively interact with whole organs. but then we’re really, really far out #stu05 | |
@ozonist @SvTwuni Yes! Btw, saw that Clinton warned earlier today about new bioweapons coming from things like this: http://bit.ly/uC688Y #stu05 |
|
@ozonist reminds me of this: http://t.co/yDDLoW9p (from @monki a while ago) | |
@doktorsbloggen @cerreyes what possibilities are there to incorporate solar cells in e.g. the windows of large glass buildings? | |
@doktorsbloggen @SvTwuni @cerreyes depends on if we are willing to accept slightly colored windows (since need to absorb visible light) or… #stu05 |
|
@doktorsbloggen @SvTwuni @cerreyes …or if we can learn to use 2 IR photons and upconvert them. So, it’s not supereasy, but probably doable #stu05 |
|
@doktorsbloggen @SvTwuni @cerreyes but the easiest way out is of course the walls of buildings, or roofs. Which is already happening #stu05 |
|
I will also take the opportunity to recommend anyone who is interested in a broader discussion on nanotech, society and culture to >> #stu05 | |
<< visit the blogg nanosocieties (http://t.co/LPM7hKXN), run by me (@jhannestad) and @karlpalmas | |
@cerreyes Thanks @doktorsbloggen @SvTwuni > Yes it’s happening… as glass facades w. solar cells http://t.co/EtsibHo0 #stu05 |
|
@ozonist @SvTwuni Okay! I think it’s time to say thank you for this very interesting hour and a half. I’ll surely tune in on nanosocieties! #stu05 |
|
@ozonist @SvTwuni I hop you can hear the clapping hands, Jonas… 🙂 #stu05 |
|
@cerreyes @doktorsbloggen @SvTwuni >By the way I was thinking in a responsive surface like DUNE but harvesting light bit.ly/uLzHLI Thxs again #stu05 |
|
and thank you @ozonist for inviting me. if there are any remaining question you can send the directly to me @jhannestad #stu05 | |
@cerreyes Thanks @jhannestad + @SvTwuni + @ozonist for another compelling tweet conference #stu05 |
|
@ozonist @SvTwuni #stu05 Yes, and you’re all welcome to continue the discussion on the http://t.co/nv0Ag3tF blog as well. Tonight’s tweets will be |
|
@ozonist @SvTwuni #stu05 put up there shortly! Thank you again, @jhannestad! |
Further reading
Light harvesting complex:
Architecture and mechanism of the light-harvesting apparatus of purple bacteria, Xiche Hu, Ana Damjanovic´, Thorsten Ritz, and Klaus Schulten
http://dx.doi.org/10.1073/pnas.95.11.5935
DNA nanotechnology:
DNA Nanotechnology and the Double Helix, Nadrian C. Seeman
http://dx.doi.org/10.1038%2Fscientificamerican0604-64 (pdf)
Challenges and opportunities for structural DNA nanotechnology, Andre V. Pinheiro, Dongran Han, William M. Shih and Hao Yan
http://dx.doi.org/10.1038/nnano.2011.187
Paul Rothemund details DNA folding
http://www.ted.com/talks/paul_rothemund_details_dna_folding.html
DNA-based photonic devices (requires journal access):
Self-Assembled DNA Photonic Wire for Long-Range Energy Transfer, Jonas K. Hannestad, Peter Sandin and Bo Albinsson
http://dx.doi.org/10.1021/ja803407t
Self-Assembled DNA-Based Fluorescence Waveguide with Selectable Output, Jonas K. Hannestad, Simon R. Gerrard, Tom Brown, Bo Albinsson
http://dx.doi.org/10.1002/smll.201101144